Journal of Spectral Imaging,   Volume 9   Article ID a2   (2020)

Peer reviewed Paper

Terahertz spectroscopy and imaging for gastric cancer diagnosis

  • Faustino Wahaia
  • Irmantas Kašalynas
  • Linas Minkevičius
  • Catia D. Carvalho Silva
  • Andrzej Urbanowicz
  • Gintaras Valušis
Department of Optoelectronics, Center for Physical Sciences and Technology, Vilnius, Lithuania

 https://orcid.org/0000-0003-1256-9424
 Search for papers by this author
Department of Optoelectronics, Center for Physical Sciences and Technology, Vilnius, Lithuania

 https://orcid.org/0000-0002-3831-8976
 Search for papers by this author
Centro Hospitalar São João, Porto, Portugal

 Search for papers by this author
Department of Optoelectronics, Center for Physical Sciences and Technology, Vilnius, Lithuania

 https://orcid.org/0000-0002-2769-452X
 Search for papers by this author
Department of Optoelectronics, Center for Physical Sciences and Technology, Vilnius, Lithuania

 https://orcid.org/0000-0002-7076-6840
 Search for papers by this author
 Corresponding Author
Universidade do Porto, Porto, Portugal
[email protected]
 https://orcid.org/0000-0001-8920-1383
 Search for papers by this author

Terahertz waves are sensitive to differences in biological tissue hydration, we present promising results regarding the feasibility of applying this with terahertz time-domain spectroscopy and imaging for early detection of cancer through the characterisation of human gastrointestinal tissue with cancer-affected regions. To do that, healthy (normal) and carcinoma-affected gastric tissue samples at different stages were measured using transmission terahertz time-domain spectroscopy in the frequency range of 0.15–2.00 THz. Absorption coefficients and refractive index spectra of both normal and carcinoma-affected tissue were extracted and analysed. The results confirm that the techniques may be powerful tools to perform qualitative, early diagnosis of human cancer.

Keywords: gastrointestinal tract, gastric carcinoma, tumour staging, terahertz waves, terahertz spectroscopy and imaging

Metrics

Downloads:

243

Full-Text HTML Views:

4

Abstract Views:

1,566